THE FLEMING UNIFIED THEORY OF HEART DISEASE - LATER KNOWN AS THE InflammoThrombotic Immunologic Response (ITIR) Disease (ITIRD) Theory.
Frequently erroneously shortened to INFLAMMATION AND HEART DISEASE THEORY
During the mid-1970's I joined the American Heart Association while at University. Soon I was actively involved in teaching and helping to develop both Basic (BCLS) and Advanced (ACLS) Cardiac (Heart) protocols to help keep people alive after their hearts had either stopped or weren't working properly.
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From there I became actively involved in trying to determine why people have heart disease. Over time it became apparent to me that heart disease, specifically disease of the arteries of the heart, is the result of the body reacting to damage occurring within the walls of the arteries and this reaction causes Inflammation. It is this Inflammation, which interferes with the ability of the arteries to work properly and results in Heart Attacks.
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It is this same Inflammation and blood clotting response, including in some instances our immune system, that can begin in one part of our body and spread throughout the body resulting in the spread of the disease or other ITIR diseases - including cancer, high blood pressure, strokes, and COVID-19.
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The following figure shows the interaction between the causes of Inflammation and Heart Disease AND it explains why people with comorbidities are dying from COVID-19. It was first presented in 1994 at the American Heart Association (AHA) Conference in Dallas, TX. It was presented at AHA again the following year (1995) and published in a Cardiology Textbook in 1999.
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Fleming RM. Chapter 64. The Pathogenesis of Vascular Disease. Textbook of Angiology. John C. Chang Editor, Springer-Verlag New York, NY. 1999, pp. 787-798. doi:10.1007/978-1-4612-1190-7_64.
Soon after presenting this theory at the AHA Conference, it became clear that my original Theory explained more than just heart disease. It also explained why we have our other chronic ITIR diseases (ITIRDs). Diseases that are both (1) increasing in frequency and (2)severity.
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These same diseases are associated with increased regional blood flow and metabolism . In other words, they are diseases which can be found, measured and treated using FMTVDM.
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In a series of papers laid out on this website and elsewhere [https://www.flemingmethod.com/], I explain how the same factors responsible for heart disease are also responsible
for:
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Heart Disease - Heart Attacks - Heart Damage,
Hypertension - High Blood Pressure,
Cancer,
Diabetes Mellitus - Impaired Insulin Receptor Response,
Autoimmune Disease,
Spontaneous Abortions,
Cerebrovascular Accidents - Strokes,
Rheumatological (arthritidies),
Gastrointestinal Disease (i.e. The "inflammatory" Ulcerative Colitis and Crohn's Disease), and
a Variety of other Chronic ITIRDs.
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As the body responds to insults from outside the body, a fine balance is maintained between health and disease.
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This balance is called homeostasis - the tendency of our bodies to respond to a problem, attempting to remove or correct the offensive insult, with failure resulting in disease and possibly death.
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During the COVID pandemic (~2019 to 2025), people frequently talked about comorbidities that were associated with worse outcomes.
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These comorbidities are not actual comorbidities. Instead they represent the disease(s) people already had due to their ITIRD precipitating factors. These ITIRD factors are shown in the figure above and briefly discussed on the following page.
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I have taken the opportunity to include a few of the slides I presented at various conferences over the last few years, during the COVID pandemic, including but not limited to https://www.flemingmethod.com/answers.
These slides are included here so you can see the relationship between these ITIRD factors and the associated disease comorbidities produced by them.
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These slides are shown in the following order:
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1) Homeostasis - The Balance Between Health & Disease,
2) The 9-Cancer Pathways - Antagonized Further by both the SARS-CoV-2 Viruses and Spike Proteins made by the Genetic Vaccines,
3) The Increase in Autoimmune Diseases Promoted by the Genetic Vaccines associated with shifts in immune responses,
4) The Relationship between these Spontaneous Abortions, and
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5) The Increase in Sudden Cardiac Death resulting from the ITIR effect of the Spike Protein, the priogenic effect of the Spike Protein and the damage to slow potassium channels of the heart caused by pseudouridine.
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Homeostasis - Blood Flow & Metabolism
Cancer
Autoimmune Disorders
Spontaneous Abortions
Sudden Cardiac Death - Heart Rhythm Stops!
