Infections Kill By Activating
The InflammoThrombotic Immunologic Response (ITIR).
If the COVID pandemic did nothing more, it should have reminded us that infections kill.
​
At the beginning of the 20th Century (1900's), the number 1 cause of death in the world was infectious disease.
​
As explained in 1994 when I first introduced the ITIR Theory [https://www.flemingmethod.com/], infections are one of the precipitating factors that can activate a series of reactions within the body producing inflammation, thrombosis (blood clotting) and our immune system.
​
When everything works properly, we get better; but, add too many factors on top of each other and the proverbial camel's back breaks - people die.
​
Two of the cardinal rules of Medicine are:
​
1) People die, and
2) Doctor's can't always change rule # 1.
​
So the discovery of penicillin by Sir Alexander Fleming was a major breakthrough in the effort to change rule #1. The use of penicillin saved countless lives.
​
Over the course of decades, people stopped dying from untreated infections and began to die from other diseases; other InflammoThrombotic Immunologic Response Diseases (ITIRDs).
​
Changes in diets and lifestyles, along with industrialization, not only reduced our physical labor; but, altered our environment, adding pollutants into our air, food, water, plants and ourselves. Some of those pollutants - or toxins if you prefer - were intentionally added to our environment and food, with some of my work in the 1970s revolving around investigating the effects of adding these toxic substances to our water; i.e. what effect would it have on living organisms?
​
While changes in the 1900s reduced our risk of dying from some ITIRD (infections), it increased our risk of dying from other ITIRDs (heart disease, high blood pressure, strokes, cancer, diabetes mellitus, et cetera).
​
During the 1980s and 1990s as I was developing the ITIRD Theory, it became clear to me, that infectious diseases, were not a thing of the past. In fact, in 1975 when The Biological Weapons Convention Treaty (BWCT) was signed, it was well understood that infectious diseases could be used - as they had over the centuries - to kill one's enemies.
​
While the leaders of countries understood the risk of infectious weapons signed the BWCT, they clearly did not understand the relationship between infections and death from the ITIR. Something we will cover more in the COVID section.
​
For now, let us turn our attention to my work in the 1980s and 1990s; work that focused on looking at the role of infectious disease and heart disease.
​
There are two basic types of cells in your body which are responsible for protecting you from infections. The first type is called a B-cell, because these cells originate in the bone marrow (inside bones) and the second type is called a T-cell because these begin in the thymus gland which is located in the center of your chest as shown in yellow.
​
B-cells are primarily responsible for attacking those infections outside your infected cells, while T-cells are primarily responsible for attacking infections occurring inside your infected cells.
To effectively protect you from infections and cancers, your B-cells and T-cells need to work together.
In fact, every time there is a new infection - e.g. SARS-CoV-2, the viral infection that caused the ITIRD, COVID-19 - the
T-cells and B-cells must work together to kill the infection and stop the disease from potentially killing you.
As it turns out, one of the many things we were taught as medical students that proved to be wrong as a result of the following research, is that the Thymus Gland shrivels up to become an atrophied non-functioning organ by the time you become a teenager. According to everything we had been taught, the thymus remains that way for the remainder of your life.
The most likely reason for this mistake, is that healthy individuals who are not fighting infections have no reason to activate their thymus gland and so to conserve and not waste energy and vital resources, when the thymus gland is not needed, it is essentially dormant. If you are only looking at people who are not fighting an infections, you will not see an active thymus gland.
​
It is also important to note, that critical heart disease, breast cancer - and probably other cancers - as well as the activated thymus gland, are only detectable and measurable using FMTVDM, during the maximal effect of pharmacologic stress, enhancing the delivery of the isotope to find regional blood flow and metabolic differences, and that time is 5-minutes after the isotope tracer has been given following peak pharmacologic stressor effect.
​
If you want to find something, you have to know where and when to look. You cannot see a bank robber rob a bank if you are not looking for them WHEN and WHERE they are robbing the bank. Similarly, you cannot find a health problem, if you are not looking at the place AND time, when you are taking advantage of the ability to expose it.
​
Activated thymus glands resulting from an infection were not discovered until I used the early versions of FMTVDM where I looked at a number of people whose heart disease had become worse during a Bacterial infection. As mentioned, this thymus activity can only seen when looking for the thymus at the right time and place - and that time is 5-minutes after injecting the enhancing agent and isotope.
​
In 1999, I began looking at people whose heart disease got worse during bacterial infections. I not only used early FMTVDM, but looked for antibodies to the infection(s),
C-reactive protein (CRP) and homocysteine (Hcy) - a marker of the body under distress [infection, early cancer, etc.] exhausting its immune system.
​
Following the identification of these people, I treated them with antibiotics based upon the infection and followed their response to antibiotic treatment. Everyone showed successful treatment of their infections with reduction of the ITIR within their body and within the arteries of their heart. Clinically this was demonstrated with a reduction in chest pain - angina.
Antibodies to the infection were produced while the thymus gland was active, demonstrating augmentation of the immune system. Following successful treatment, both CRP and Hcy levels normalized, while coronary artery blood flow improved. The results showed that treating the infection not only killed the bacteria but reduced the ITIR occurring within the arteries of the heart.
​
The following example shows one of the study patients shows with an activated thymus gland before treatment on 8 June 1999. The arrow in the upper left panel points to the activated thymus gland, which is no longer activated several weeks later (upper right panel).
​
The decreased areas of blood flow to the heart before treatment are shown in the left lower panel. These areas are green and are noted by the white arrows. Following treatment, these areas showed improvement in blood flow, transitioning to less ITIRD as shown by the color change.
The recognition that viruses, bacteria and other infectious agents can worsen the ITIRD present in the arteries of the heart and elsewhere in the body, resulted in the following Letter to the Editor being published in 2000, where I cautioned that failure to address the ITIR associated with infections, could lead to worsening of the underlying diseases, deteriorating health and potential death.
Several years later, in the Journal of Clinical Investigations, researchers from NIH and the National Cancer Institute published a paper showing "thymic regrowth" was essential to maintaining the body's T-cell population. Confirmation of yet another component of the ITIRD Theory & FMTVDM.
