A few of my specific contributions to Medical Science.

During the last 50+ years I have had the good fortune to be trained by some of the best minds in physics, chemistry, biology, medicine and psychology.

My resulting research has included:

1) Control and regulation of plasma-positron annihilation,

2) Laser and Maser developments,

3) Determination of the impact of shale products on living organisms,

4) Cisplatin and DNA impact including chemical analysis,

5) The psychological impact of unconscious messaging - including Industrial and Intelligence Psychology experiments,

6) The impact of sodium on erythrocyte Ouabain receptors and peroneal nerve recording and differentiation of sympathetic and parasympathetic differentiation,

7) Phosphodiesterase Inhibitors and the treatment of various forms of heart failure,

8) Treatment of lipid abnormalities,

9) Work with Dr. Mel Marcus and cine-computed tomography,

10) Work with White and Wilson on intravascular ultrasound (IVUS),

11) Specialized training and certified in PET and SPECT imaging with the development of rapid image acquisition using a priori definitions of tissue differences to study the consequences of drug use, including tetrahydrocannabinol (THC; research grade; MKUltra follow up work) upon the brain,

12) Development and publication of the new technetium-99m isotopes and PET isotopes including but not limited to FDG, Rubidium-82 and 13N-Ammonia,

12) Multiple dietary studies to determine the outcome effects on heart disease and cancer,

13) The development of the Fleming Unified Theory of Vascular Disease which ultimately came to be known as the InflammoThrombotic Immunologic Response Disease (ITIRD) Theory, and

14) The Fleming Method for Tissue and Vascular Differentiation and Metabolism (FMTVDM) Using Same State Single or Sequential Quantification Comparisons. [US9566037B2].

The use of FMTVDM and The ITIRD expanded my ability to detect changes in tissue sooner than previously possible, as well as define the extent and severity of health problems, in addition to being able to measure whether a specific treatment works for a particular person - ultimately saving time, money, resources and lives.

Some of the contributions to Medical science made possible by this combination include:

A) Demonstrating the ability to reverse coronary artery disease,

B) Demonstrated for the first time the abilty to restore damaged heart tissue. Specifically, the ability to restore the function of stunned and/or hibernating myocardium. In other words, the recovery of heart tissue that had not yet completely died, but was no longer working due to deprived blood and nutrients. By reversing the ITIR causing the coronary artery disease (ITIRD), the stunned and/or hibernating myocardium, recovered and began to work once more. Thus, reducing the person's heart failure.

C) Demonstrated for the first time the role that bacteria and other infectious diseases play in causing ITIRDs, as well as demonstrating that the thymus gland, once thought to be inactive following adolescence, actually becomes metabolically active during periods of infectious disease, only to once again become less active and return to a less metabolically active state, once the infectious process had resolved and the need for enhanced thymic activity had passed.

This understanding was furthered during the COVID pandemic when the viral infections (SARS-CoV-2) and the genetic vaccine consequences (ITIRD to spike protein) were measured; including treatment responses.

D) Demonstrated for the first time the use of female hormone therapy [HRT] is associated with unhealthy changes in female breast tissue, resulting in early cancerous changes,

E) Demonstrated for the first time that not all drugs or products work equally in treating health problems by measuring changes following treatment. E.g. some women showed improvement in breast health with the use of soy protein products, while others showed progression of breast disease - i.e. some women get better while others get worse.

F) Demonstrated for the first time that our nuclear cameras designed to find disease, actually miss 35% of the available information coming from the patient. This is the result of nuclear camera companies failing to understand that simply seeing energy coming from the patient doesn't mean all the information is being detected by the camera; introducing error.

While the nuclear camera companies have spent time improving the appearance of the images, by increasing the number of pixels for resolution, this has introduced problems with modulation transfer function (MTF) and fourier transfer data loss. As a result, visually interpreted images (qualitative imagine) is being made by physicians without 1/3rd of the actual information that should be received by the nuclear camera's computer system.

G) Demonstrated for the first time that the isotopes being used for our nuclear imaging, do not need to be given twice when looking for heart disease. In fact, FMTVDM demonstrated that these isotopes move around (redistribute) and only need to be given once.

Demonstrating that the current protocols encouraged by Big Pharma, while increasing Big Pharma sales and profits, result in misdiagnosis and increased patient radiation exposure. [https://www.flemingmethod.com/about]

H) Developed the coronary blood flow equation detailing and describing what variables (entry angle into lumen narrowing, exit angle from lumen narrowing, length, density of imaging data, diameter lumen narrowing/stenosis at two different pints 90 degrees apart and the overall area stenosis) that determine how severe the coronary artery disease (CAD) truly is in addition to the effect this has on the ability of coronary arteries to relax (flow reserve) to increase blood flow to the heart when the heart needs more blood to work.

I) Demonstrated for the first time that the pain [angina; angina pectoris] resulting from coronary artery disease (CAD; ITIRD) is not due to a narrowed coronary lumen (area where the blood flows) - although a narrowed coronary lumen can further precipitate angina; but rather, that angina is the result of differences in coronary artery regional blood flow; i.e. differences in flow reserve between the arteries.

Most treatments including laser therapy (transmyocardial laser revascularization), coronary artery bypass grafting (CABG), medications, et cetera, result in a sharing of blood flow from the good flow areas to the poorer blood flow areas. As a consequence, the overall blood flow to the heart is NOT improved; but, good areas are compromised to feed poorer blood flow (diseased) areas.

The ultimate goal of course, should be to improve overall coroanry blood flow AND this is only possible by reversing coronary artery disease, which as I and others have shown, is only possible through diet and lifestyle changes.

Thus the need to truly quantify with FMTVDM what treatments reverse heart disease and which merely mask it.

J) Demonstrated for the first time, that using blood tests and/or changes in weight, do NOT tell you what is happening at the tissue level, where the actual disease is at.

K) Demonstrated for the first time that the first changes in blood tests indicative of the development of a failing immune system and cancer, is an increase in homocysteine (Hcy) levels. Although, these changes in Hcy follow changes seen on FMTVDM.

L) Demonstrated for the first time that removal of a primary cancer results in the loss of primary cancer inhibitors that control/inhibit the growth of smaller cancers. Once the primary (larger) cancer is removed, smaller cancers are no longer inhibited and later appear as new or recurrent cancers. These smaller cancers show inhibition with FMTVDM.

M) Demonstrated for the first time that errors made in reading coronary angiograms performed during cardiac catherterization are the result of physician reading errors. Errors that can be reduced by training physicians to ignore what they think they are seeing and quantifying (measuring) the images.

This means that while weight and blood tests provide some information, they do not tell you what you need to know - are you truly getting better, are your treatments working, or are you just fooling yourself?

The following research papers and publications provide some of the background on these contributions to Medical Science.