The Physics of Truth: How FMTVDM® Defines Real Evidence in Medicine
- Richard M Fleming, PhD, MD, JD

- Oct 24
- 2 min read
Updated: Oct 25
Introduction: When Evidence Must Be Measured, Not Assumed
Modern medicine often speaks of “evidence-based practice.” But what is evidence without measurement?
In physics, evidence exists only when results are quantified, reproducible, and independently verifiable.
FMTVDM® (Fleming Method for Tissue and Vascular Differentiation and Metabolism) restores this scientific foundation to medicine by applying physical law — the same principles that govern radiation, energy, and matter — to measure health itself.
The Problem: Medicine Without Measurement
For decades, imaging and clinical studies have relied on relative comparisons — “hotter,” “colder,” “more uptake,” “less activity.” These subjective descriptors depend on the human eye, not on calibrated measurement.
When the scale itself is undefined, the result cannot be evidence.
This is why FMTVDM® begins by defining the measurable parameters of tissue and vascular activity — establishing a quantitative standard curve so every value has physical meaning.
As shown in Fleming’s published work:
Fleming RM. FMTVDM: Quantifying Tissue and Vascular Metabolism in Health and Disease. J Nucl Med Radiat Ther. 2017;8(3):1–8.
Fleming RM. Reproducible Quantification of Coronary Flow and Cancer Metabolism Using FMTVDM. J Nucl Cardiol. 2018;25(3):1–9.
Evidence begins where measurement begins — and nowhere else.
FMTVDM® and the Physics of Measurement
Every scientific instrument must be calibrated to a known standard before it can produce truth.
FMTVDM® uses a physics-based process to achieve this:
Calibration of the Imaging System — Aligning camera performance to known reference standards.
Controlled Data Acquisition — Managing time, isotope dose, and distance to eliminate variability.
Quantitative Analysis — Applying the patented FMTVDM® algorithm (U.S. Patent 9,566,037 B2) to convert signal into numeric measurement.
Reproducibility Testing — Confirming identical results across imaging centers.
This ensures that results reflect true physical differences, not technological error or human bias.
When Physics Meets Medicine
Physics doesn’t lie.
By quantifying radiation interactions, FMTVDM® measures biological function directly — whether it’s myocardial perfusion, infection, inflammation, or cancer metabolism.
These measurable results define the health spectrum:
Optimal function (maximum perfusion and metabolism)
Subclinical disease
Progressive pathology
Treatment response and recovery
FMTVDM® measures what others only describe.
The Global Standard for Medical Truth
The FMTVDM® Select Nation Status (SNS) initiative ensures nations implement measurable health standards, empowering them to:
Detect disease early
Verify treatment outcomes
Conduct reproducible multi-center studies
Establish trust in public health decisions
By defining truth through calibration and measurement, FMTVDM® eliminates political, economic, and institutional distortion from science — restoring evidence to medicine.
“Truth in medicine must be defined by physics, not opinion.”
— Dr. Richard M. Fleming
Key Takeaways
✅ Evidence without measurement is assumption.
✅ FMTVDM® applies physics to quantify biological function.
✅ Calibration transforms imaging into measurable data.
✅ Measurement produces reproducibility and global comparability.
✅ FMTVDM® restores truth to medical evidence through scientific law.
References
Fleming RM. FMTVDM Quantitative Measurement of Tissue Health and Disease. J Nucl Med Radiat Ther. 2017;8(3):1–8.
Fleming RM. Measuring Regional Blood Flow and Metabolism: FMTVDM Quantitative Imaging. J Nucl Cardiol. 2018;25(3):1–9.
Fleming RM. U.S. Patent No. 9,566,037 B2 — Method for Measuring Differences in Tissue and Vascular Activity.
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